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There is no episode where Brick from The Middle gets skinned alive, as that's a violent event not depicted in the family sitcom; however, a similar-sounding plot point involves Brick being accidentally switched at birth with another baby for a month, revealed in the Season 2 episode, "The District" (Episode 7), where he was left with the wrong family, reports a Facebook post.
The Actual Event: In "The District" (S2, E7), it's discovered Brick was swapped at birth and lived with another family for a month before the mix-up was corrected, a common sitcom trope, not a violent incident.
Misremembering: The "skinned alive" idea might stem from confusion with extreme horror themes or a misunderstanding of Brick's unusual nickname, which is tied to his love of books and a story about being "brick-headed," not violence.